Clinical Study
CPHA5030
Our best-selling combination of 5.000 mg of TOSLA selected Collagen peptides and 30 mg of hyaluronic acid, offering superb hydration and skin texture improvements.
Additionally, 80 mg of vitamin C is added to the formulation which is sugar free and comes in an easy-to-use liquid format.
Produced with VELIOUS™ flavor technology.
5.000 mg
COLLAGEN PEPTIDES
+
30 mg
HYALURONIC ACID
+
80 mg
VITAMIN C
CPHA5030
Our best-selling combination of 5.000 mg of TOSLA selected Collagen peptides and 30 mg of hyaluronic acid, offering superb hydration and skin texture improvements.
Additionally, 80 mg of vitamin C is added to the formulation which is sugar free and comes in an easy-to-use liquid format.
Produced with VELIOUS™ flavor technology.
5.000 mg
COLLAGEN PEPTIDES
+
30 mg
HYALURONIC ACID
+
80 mg
VITAMIN C
Collagen
Stimulation
Supplemented collagen peptides mimic the breakdown of the skin’s own collagen, triggering fibroblasts in the dermis to produce new collagen molecules.
Hyaluronic Acid-Powered Hydration
Hyaluronic acid, a naturally occurring molecule in the skin, works with collagen to boost moisture retention. It binds water molecules, promoting skin elasticity and plumpness, while vitamin C assists by protecting the skin from oxidative stress and supporting overall collagen formation.
Synergistic Benefits and
Consumer Appeal
Combining collagen peptides and hyaluronic acid enhances skin hydration, improves dermis density, and reduces wrinkles. This powerful duo rejuvenates the skin’s appearance and appeal.
What can customer expect?
Week 4
By the fourth week, you are nourishing your skin with essential ingredients that support hydration and repair. Regular intake has led to visible improvements in hydration and the first signs of elasticity enhancement.
Week 8
At the eight-week mark, your skin feels firmer and smoother. There is a significant reduction in fine lines, and the overall tone and texture are more even and radiant, boosting your confidence and satisfaction.
Clinically
proven
Significant improvement in skin hydration, structure and texture, which directly translates into wrinkles depth and volume reduction in just 16 weeks.
+1,5%
Dermis thickness
-3,3%
Skin roughness
+110%
Skin hydration
-15,4%
Wrinkles depth
+22%
Dermis density
-11,1%
Wrinkles volume
Ingredients
We source our collagen peptides from upcycled fish and bovine skin in the EU. We have developed specific acceptance criteria and devolved special attention to potency, adequate hydrolysation level, low heavy metals content, and more.
Collagen peptides
Hyaluronic acid
Xylitol
Vitamin C
TOSLA blend
Collagen peptides
Hyaluronic acid
Xylitol
Vitamin C
TOSLA blend
Designed
to taste great
Next to high performance, user experience of your end customers are at the most importance for us.
Thanks to TOSLA’s patented VELIOUS™ flavor technology, the two ingredients known for their unpleasant flavor can be combined with ease, without sacrificing the palatability of the end product.
The Clinical Proof
Study Formulation
Clinical study examined the formulation with 5.000 mg of TOSLA selected Collagen peptides, 30 mg of hyaluronic Acid, and 80 mg of Vitamin C, produced with VELIOUS™ technology.
Study Design
An independent institute conducted a randomized, double-blind, placebo-controlled study with 87 women aged 40-65, BMI under 35.
Study Objective
Primary endpoints of the study were evaluating the capability of test products to promote the synthesis of collagen and elastin fibres in the dermal layer of the skin.
15 ml
Daily intake
87
Women
16
Weeks
Study Results
CPHA5030
Liquid Formulation
22%
improvement
in dermis density
Losing skin density manifests in sagging, fine lines and wrinkles.
Skin density is the combination of collagen and elastin, along with other lipids and amino acids, that create the matrix of the dermis.
The clinical study showed a significant, 22% improvement in dermis density using a Collagen and Hyaluronic Acid combination.
Effects of intervention on dermis
Ultrasound images of the dermis at baseline and after 16 weeks.
The Clinical Proof
Study Formulation
Clinical study examined the formulation with 5.000 mg of TOSLA selected Collagen peptides, 30 mg of hyaluronic Acid, and 80 mg of Vitamin C, produced with VELIOUS™ technology.
Study Design
An independent institute conducted a randomized, double-blind, placebo-controlled study with 87 women aged 40-65, BMI under 35.
Study Objective
Primary endpoints of the study were evaluating the capability of test products to promote the synthesis of collagen and elastin fibres in the dermal layer of the skin.
15 ml
Daily intake
107
Women
16
Weeks
Study Results
CPHA5030
Liquid Formulation
22%
improvement
in dermis density
Losing skin density manifests in sagging, fine lines and wrinkles.
Skin density is the combination of collagen and elastin, along with other lipids and amino acids, that create the matrix of the dermis.
The clinical study showed a significant, 22% improvement in dermis density using a Collagen and Hyaluronic Acid combination.
Effects of intervention on dermis
Ultrasound images of the dermis at baseline and after 16 weeks.
In the ultrasound images, the white line to the left represents the epidermis with a water film, to the right followed by dermis, characterized by varying intensities, and subcutis by low-intensity areas due to a homogenous composition.
An increase in dermis echogenicity is visible, indicating an improvement in dermal density throughout the study, while no important change can be observed from images for subject from placebo group.
1,5%
improvement
in dermis thickness
Losing dermis thickness causes loss of skin elasticity.
Genetics undoubtedly contribute to the problem of thin skin, but
ultraviolet light (sun & tanning beds) actually has the biggest impact on thinning our skin.
Losing thickness of our skin is one of the toughest things to reverse due to regular light exposure, so a 1,5% improvement in only 16 weeks is a significant achievement.
110%
improvement
in skin hydration
Hydration is key in preventing the premature appearance of wrinkles.
Your skin needs water to give it strength and elasticity – in other words, to look and feel healthy.
Skin hydration consequently represents a huge category in skin cosmetics.
The study showed a significant, 110% increase in skin hydration using collagen supplementation for just 16 weeks.
-3,3%
decrease
in skin roughness (Ra)
Skin hydration and roughness are highly connected.
The study showed, that thanks to highly improved skin hydration using a collagen and hyaluronic acid combination, skin roughness decreased 3,3% as well.
Effects of intervention
on skin roughness (Ra)
Visuals from a subject’s cheek area using the Antera 3D texture mode.
Roughness is quantified by the vertical deviations of a real surface from its ideal form. If these deviations are large, the surface is rough; if they are small the surface is smooth.
A false-color map is used to identify the areas with textural roughness, where red and yellow colours represent depressed areas, and blue and purple colours represent elevated areas.
-15,4%
wrinkle max. depth
-11,1%
wrinkle volumes
With thinner, less hydrated, and less elastic skin, the wrinkles appear.
With age, we lose skin thickness and density, skin is less hydrated and elastic, therefore the natural process of wrinkling begins.
The study shows that we can reverse this process with collagen supplementation. In fact there was an improvement of 15,4% in maximum wrinkle depth and 11,1% in wrinkle volumes after 16 weeks.
Effects of intervention
on wrinkles
Visuals from a subjects’ Crow’s feet area.
Visuals from a subjects’ Crow’s feet area using the medium filter from the Antera 3D wrinkles mode. In the false color map, dark red indicates the deepest features
and white corresponds to the top of
the skin surface.