Clinical Study
CPM6500
Synergy of collagen and MSM, resulting in improved skin texture and hydration + reduced wrinkles and fine lines.
Produced with VELIOUS™ flavor technology.
Formulation is sugar free and comes in a liquid format which provides special convenience and ease of use.
5.000 mg
COLLAGEN PEPTIDES
+
1.500 mg
methylsulphonylmethane (MSM)
Produced with:
VELIOUS™
FLAVOR TECHNOLOGY
CPM6500
Synergy of collagen and MSM, resulting in improved skin texture and hydration + reduced wrinkles and fine lines.
Produced with VELIOUS™ flavor technology.
Formulation is sugar free and comes in a liquid format which provides special convenience and ease of use.
5.000 mg
COLLAGEN PEPTIDES
+
1.500 mg
methylsulphonylmethane (MSM)
Produced with:
VELIOUS™
FLAVOR TECHNOLOGY
Collagen
Stimulation
Supplemented collagen peptides mimic the breakdown of the skin’s own collagen, triggering fibroblasts in the dermis to produce new collagen molecules.
Sulfur-Powered
Synthesis
MSM, a sulfur-rich ingredient with powerful antioxidative and anti-inflammatory properties, plays a fundamental role
in synthesizing collagen, hyaluronic acid,
and keratohyalin, thus accelerating
these processes.
Synergistic Benefits and
Consumer Appeal
Formulated together, these ingredients provide a synergistic effect that improves skin texture and reduces wrinkles and fine lines. The attractive price point and high performance make this formulation a popular choice among consumers.
What can customer expect?
Month 1
You started feeding your skin with essentials that help nurture and restore it. Consistency is key to reaching skin wellness.
Month 2
The state of your skin is starting to improve, manifesting in first visible results in wrinkles reduction and texture improvement.
Month 3
A new structure and texture of your skin is starting to sink in. New joy and confidence are found in this improved appearance.
Clinically
proven
Significant improvement in skin structure and texture, which directly translates into wrinkles depth and volume reduction in just 12 weeks.
+3,6%
Dermis thickness
-12%
Skin roughness
+32%
Skin hydration
-14%
Wrinkles depth
+20%
Dermis density
-12%
Wrinkles volume
Ingredients
We source our collagen peptides from upcycled fish and bovine skin in the EU. We have developed specific acceptance criteria and devolved special attention to potency, adequate hydrolysation level, low heavy metals content, and more.
Collagen peptides
MSM
Xylitol
Vitamin C
TOSLA blend
Collagen peptides
MSM
Xylitol
Vitamin C
TOSLA blend
Designed
to taste great
Next to high performance, user experience of your end customers are at the most importance for us.
Thanks to TOSLA’s patented VELIOUS™ flavor technology, the two ingredients known for their unpleasant flavor can be combined with ease, without sacrificing the palatability of the end product.
The Clinical Proof
Study Formulation
Clinical study examined the formulation with 5.000 mg of TOSLA selected Collagen peptides and 1.500 mg of MSM, produced with VELIOUS™ technology.
Study Design
An independent institute conducted
a randomized, double-blind,
placebo-controlled study with 27 women aged 40-65, BMI under 35.
Study Objective
Primary endpoints of the study were evaluating the capability of test products to promote the synthesis of collagen and elastin fibres in the dermal layer of the skin.
25 ml
Daily intake
107
Women
12
Weeks
Study Results
Collagen 5.000 + MSM
Liquid Formulation
20%
improvement
in dermis density
Losing skin density manifests in sagging, fine lines and wrinkles.
Skin density is the combination of collagen and elastin, along with other lipids and amino acids, that create the matrix of the dermis.
The clinical study showed a significant, 20% improvement in dermis density using a Collagen and MSM combination.
Effects of intervention on dermis
Ultrasound images of the dermis at baseline and after 12 weeks
The Clinical Proof
Study Formulation
Clinical study examined the formulation with 5.000 mg of TOSLA selected Collagen peptides and 1.500 mg of MSM, produced with VELIOUS™ technology.
Study Design
An independent institute conducted
a randomized, double-blind,
placebo-controlled study with 27 women aged 40-65, BMI under 35.
Study Objective
Primary endpoints of the study were evaluating the capability of test products to promote the synthesis of collagen and elastin fibres in the dermal layer of the skin.
25 ml
Daily intake
87
Women
12
Weeks
Study Results
Collagen 5.000 + MSM
Liquid Formulation
20%
improvement
in dermis density
Losing skin density manifests in sagging, fine lines and wrinkles.
Skin density is the combination of collagen and elastin, along with other lipids and amino acids, that create the matrix of the dermis.
The clinical study showed a significant, 20% improvement in dermis density using a Collagen and MSM combination.
Effects of intervention on dermis
Ultrasound images of the dermis at baseline and after 12 weeks.
In the ultrasound images, the white line to the left represents the epidermis with a water film, to the right followed by dermis, characterized by varying intensities, and subcutis by low-intensity areas due to a homogenous composition.
An increase in dermis echogenicity is visible, indicating an improvement in dermal density throughout the study, while no important change can be observed from images for subject from placebo group.
3,6%
improvement
in dermis thickness
Losing dermis thickness causes loss of skin elasticity.
Genetics undoubtedly contribute to the problem of thin skin, but ultraviolet light (sun & tanning beds) actually has the biggest impact on thinning our skin.
Losing thickness of our skin is one of the toughest things to reverse due to regular light exposure, so a 3,6% improvement in only 12 weeks is a significant achievement.
32%
improvement
in skin hydration
To prevent the premature appearance of wrinkles, skin hydration is crucial.
Your skin needs water to give it strength and elasticity – in other words, to look and feel healthy.
Skin hydration consequently represents a huge category in skin cosmetics.
The study showed a significant, 32% increase in skin hydration using Collagen supplementation for just 12 weeks.
12%
Improvement
in skin roughness
MSM addition doubles facial skin roughness improvement.
The clinical study showed a significant, 12% difference in skin roughness using a Collagen and MSM combination even compared to a higher concentrated collagen-only supplement.
The addition of MSM in the formulation doubles the skin roughness improvement comparing to only collagen supplementation.
Effects of intervention
on skin roughness (Ra)
Visuals from a subject’s cheek area using the Antera 3D texture mode.
Roughness is quantified by the vertical deviations of a real surface from its ideal form. If these deviations are large, the surface is rough; if they are small the surface is smooth.
A false-color map is used to identify the areas with textural roughness, where red and yellow colours represent depressed areas, and blue and purple colours represent elevated areas.
-14%
wrinkle max. depth
-12%
wrinkle volumes
With thinner, less hydrated, and less elastic skin, the wrinkles appear.
With age, we lose skin thickness and density, skin is less hydrated and elastic, therefore the natural process of wrinkling begins.
The study shows that we can reverse this process with collagen supplementation. In fact there was an improvement of 14% in maximum wrinkle depth and 12% in wrinkle volumes after 12 weeks.
Effects of intervention
on wrinkles
Visuals from a subjects’ Crow’s feet area.
Roughness is quantified by the vertical deviations of a real surface from its ideal form. If these deviations are large, the surface is rough; if they are small the surface is smooth.
A false-color map is used to identify the areas with textural roughness, where red and yellow colours represent depressed areas, and blue and purple colours represent elevated areas.